International Journal of Immunology

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The Beneficial Effects of L. reuteri Probiotics in Development of the Toddlers' Immune Systems and Gut Health in Bangladesh

Received: 14 September 2023    Accepted: 4 October 2023    Published: 30 October 2023
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Abstract

A well-researched probiotic bacteria called Lactobacillus reuteri (L. reuteri) has the ability to colonize several animals. L. reuteri can be found in the skin, breast milk, urinary tract, gastrointestinal tract, and other parts of the human body. Different people have varying amounts of L. reuteri. There are a number of advantages to L. reuteri. First, L. reuteri has the ability to create compounds that are antimicrobial, such as organic acids, ethanol, and reuteri. L. reuteri's antimicrobial activity enables it to prevent the colonization of pathogenic bacteria and alter the composition of the host's commensal microbiota. Second, L. reuteri can strengthen the immune system of the host. For instance, some L. reuteri strains can enhance the formation and activity of regulatory T cells while suppressing the production of pro-inflammatory cytokines. Third, because L. reuteri has the possibility to fortify the intestinal barrier, its colonization may lessen the number of bacteria that move from the gut lumen to tissues. It has been proposed that microbial translocation across the gut epithelium causes inflammation to start. Therefore, boosting the colonization of L. reuteri may help to alleviate inflammatory illnesses, including those that affect the gut as well as distant organs. Notably, during the past few decades, L. reuteri abundance in humans has declined, and at the same time, inflammatory illness occurrences in toddlers have increased. For the correct developmental growth of toddlers, obvious supplementation, or prebiotic modification of L. reuteri may be an alluring preventative and/or therapeutic pathway counter to inflammatory illnesses.

DOI 10.11648/j.iji.20231102.12
Published in International Journal of Immunology (Volume 11, Issue 2, June 2023)
Page(s) 17-28
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Lactobacillus Reuteri, Microbiota, Probiotic, Immune System, Inflammatory Diseases, Toddler, Gut Health

References
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    Sultana Begum, Archana Dev, Nurul Alam Khan, Ranjith Debnath, Mozammel Haque, et al. (2023). The Beneficial Effects of L. reuteri Probiotics in Development of the Toddlers' Immune Systems and Gut Health in Bangladesh. International Journal of Immunology, 11(2), 17-28. https://doi.org/10.11648/j.iji.20231102.12

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    ACS Style

    Sultana Begum; Archana Dev; Nurul Alam Khan; Ranjith Debnath; Mozammel Haque, et al. The Beneficial Effects of L. reuteri Probiotics in Development of the Toddlers' Immune Systems and Gut Health in Bangladesh. Int. J. Immunol. 2023, 11(2), 17-28. doi: 10.11648/j.iji.20231102.12

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    AMA Style

    Sultana Begum, Archana Dev, Nurul Alam Khan, Ranjith Debnath, Mozammel Haque, et al. The Beneficial Effects of L. reuteri Probiotics in Development of the Toddlers' Immune Systems and Gut Health in Bangladesh. Int J Immunol. 2023;11(2):17-28. doi: 10.11648/j.iji.20231102.12

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  • @article{10.11648/j.iji.20231102.12,
      author = {Sultana Begum and Archana Dev and Nurul Alam Khan and Ranjith Debnath and Mozammel Haque and Mohammad Amjad Hossain and Mohammad Sakhawat Hossain and Rakibul Hasan},
      title = {The Beneficial Effects of L. reuteri Probiotics in Development of the Toddlers' Immune Systems and Gut Health in Bangladesh},
      journal = {International Journal of Immunology},
      volume = {11},
      number = {2},
      pages = {17-28},
      doi = {10.11648/j.iji.20231102.12},
      url = {https://doi.org/10.11648/j.iji.20231102.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20231102.12},
      abstract = {A well-researched probiotic bacteria called Lactobacillus reuteri (L. reuteri) has the ability to colonize several animals. L. reuteri can be found in the skin, breast milk, urinary tract, gastrointestinal tract, and other parts of the human body. Different people have varying amounts of L. reuteri. There are a number of advantages to L. reuteri. First, L. reuteri has the ability to create compounds that are antimicrobial, such as organic acids, ethanol, and reuteri. L. reuteri's antimicrobial activity enables it to prevent the colonization of pathogenic bacteria and alter the composition of the host's commensal microbiota. Second, L. reuteri can strengthen the immune system of the host. For instance, some L. reuteri strains can enhance the formation and activity of regulatory T cells while suppressing the production of pro-inflammatory cytokines. Third, because L. reuteri has the possibility to fortify the intestinal barrier, its colonization may lessen the number of bacteria that move from the gut lumen to tissues. It has been proposed that microbial translocation across the gut epithelium causes inflammation to start. Therefore, boosting the colonization of L. reuteri may help to alleviate inflammatory illnesses, including those that affect the gut as well as distant organs. Notably, during the past few decades, L. reuteri abundance in humans has declined, and at the same time, inflammatory illness occurrences in toddlers have increased. For the correct developmental growth of toddlers, obvious supplementation, or prebiotic modification of L. reuteri may be an alluring preventative and/or therapeutic pathway counter to inflammatory illnesses.
    },
     year = {2023}
    }
    

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    T1  - The Beneficial Effects of L. reuteri Probiotics in Development of the Toddlers' Immune Systems and Gut Health in Bangladesh
    AU  - Sultana Begum
    AU  - Archana Dev
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    AU  - Ranjith Debnath
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    AU  - Mohammad Amjad Hossain
    AU  - Mohammad Sakhawat Hossain
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    T2  - International Journal of Immunology
    JF  - International Journal of Immunology
    JO  - International Journal of Immunology
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    EP  - 28
    PB  - Science Publishing Group
    SN  - 2329-1753
    UR  - https://doi.org/10.11648/j.iji.20231102.12
    AB  - A well-researched probiotic bacteria called Lactobacillus reuteri (L. reuteri) has the ability to colonize several animals. L. reuteri can be found in the skin, breast milk, urinary tract, gastrointestinal tract, and other parts of the human body. Different people have varying amounts of L. reuteri. There are a number of advantages to L. reuteri. First, L. reuteri has the ability to create compounds that are antimicrobial, such as organic acids, ethanol, and reuteri. L. reuteri's antimicrobial activity enables it to prevent the colonization of pathogenic bacteria and alter the composition of the host's commensal microbiota. Second, L. reuteri can strengthen the immune system of the host. For instance, some L. reuteri strains can enhance the formation and activity of regulatory T cells while suppressing the production of pro-inflammatory cytokines. Third, because L. reuteri has the possibility to fortify the intestinal barrier, its colonization may lessen the number of bacteria that move from the gut lumen to tissues. It has been proposed that microbial translocation across the gut epithelium causes inflammation to start. Therefore, boosting the colonization of L. reuteri may help to alleviate inflammatory illnesses, including those that affect the gut as well as distant organs. Notably, during the past few decades, L. reuteri abundance in humans has declined, and at the same time, inflammatory illness occurrences in toddlers have increased. For the correct developmental growth of toddlers, obvious supplementation, or prebiotic modification of L. reuteri may be an alluring preventative and/or therapeutic pathway counter to inflammatory illnesses.
    
    VL  - 11
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Author Information
  • Department of Paediatric, North East Medical College Hospital, Sylhet, Bangladesh

  • Department of Paediatric, Jalalabad Ragib Rabeya Medical College Hospital, Sylhet, Bangladesh

  • Department of Paediatric, Red Crescent Matrimongol Hospital, Sylhet, Bangladesh

  • Department of Paediatric, Lion Children Hospital, Sylhet, Bangladesh

  • Department of Paediatrics, 250 Bedded Moulvibazar Sadar Hospital, Sylhet, Bangladesh

  • Department of Paediatrics, The Labaid Specialized Hospital, Brahmanbaria, Bangladesh

  • Department of Paediatrics, 250 Bedded General Hospital, Kishoreganj, Bangladesh

  • Department of Paediatrics, Christian Medical Center, Brahmanbaria, Bangladesh

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